| 1 | Panama City , Panama | 408,168 | 8.994 / -79.520 |
| 2 | San Miguelito , Panama | 321,501 | 9.050 / -79.471 |
| 3 | Juan Díaz , Panama | 100,636 | 9.041 / -79.441 |
| 4 | David , Chiriqui | 82,907 | 8.427 / -82.431 |
| 5 | Colón , Colon | 78,000 | 9.360 / -79.900 |
| 6 | Arraiján , Panamá Oeste Province | 76,815 | 8.940 / -79.640 |
| 7 | La Chorrera , Panamá Oeste Province | 61,232 | 8.878 / -79.780 |
| 8 | Tocumen , Panama | 50,844 | 9.089 / -79.383 |
| 9 | Santiago de Veraguas , Veraguas | 45,355 | 8.100 / -80.983 |
| 10 | Chilibre , Panama | 33,536 | 9.154 / -79.620 |
| 11 | Cativá , Colon | 29,607 | 9.362 / -79.832 |
| 12 | Ancón , Panama | 20,706 | 8.960 / -79.551 |