| Name | Country | Feature class | Latitude | Longitude | |
|---|---|---|---|---|---|
451  | Alto del Espino  Alto del Espino | Panama, Panamá Oeste Province La Chorrera District > Corregimiento Feuillet | section of populated place population 3,672 | N 8° 50′ 49'' | W 79° 50′ 27'' |
| 452 | Alcalde Díaz Alcalde Diaz,Alcalde Díaz,Alcaldediaz,Alcaldedíaz,Penoncito,Peñoncito | Panama, Panamá Panamá District > Alcalde Diaz | seat of a third-order administrative division population 20,285 | N 9° 7′ 21'' | W 79° 33′ 24'' |
| 453 | Alanje Alanje | Panama, Chiriquí Province Alanje District > Corregimiento Alanje | seat of a second-order administrative division population 1,373 | N 8° 23′ 59'' | W 82° 33′ 31'' |
| 454 | Aguadulce Aguadulce | Panama, Coclé Aguadulce District > Corregimiento Aguadulce | seat of a second-order administrative division population 8,501 | N 8° 14′ 29'' | W 80° 32′ 23'' |
| 455 | Acuatupu Acuatupo,Acuatupo No. 1,Acuatupo Numero Uno,Acuatupo Número Uno,Acuatupu,Isla Piedra | Panama, Guna Yala El Porvenir > Nargana | populated place | N 9° 27′ 21'' | W 78° 59′ 54'' |
| 456 | Tonosí Tonosi,Tonosí | Panama, Los Santos Province Tonosí District > Corregimiento Tonosí | seat of a second-order administrative division population 1,478 | N 7° 24′ 25'' | W 80° 26′ 21'' |
| 457 | Tolé Tole,Tolé | Panama, Chiriquí Province Tolé District > Corregimiento Tolé | seat of a second-order administrative division population 2,794 | N 8° 14′ 35'' | W 81° 40′ 11'' |
| 458 | Tijeras Tijera,Tijeras | Panama, Chiriquí Province Boquerón District > Tijeras | seat of a third-order administrative division population 1,148 | N 8° 28′ 9'' | W 82° 32′ 54'' |
| 459 | Ticantiquí Matupo,Niatupo,TJC,Ticantiqui,Ticantiquí | Panama, Guna Yala El Porvenir > Nargana | populated place | N 9° 25′ 0'' | W 78° 29′ 0'' |
460  | Isla Taborcillo Isla Taborcillo,Tabor Island | Panama, Panamá Oeste Province | island | N 8° 40′ 23'' | W 79° 44′ 30'' |
| 461 | Taboga Island Taboga Island | Panama, Panamá | island | N 8° 47′ 22'' | W 79° 33′ 27'' |
| 462 | Sortová Sortoua,Sortova,Sortová | Panama, Chiriquí Province Bugaba District > Corregimiento Sortová | seat of a third-order administrative division population 1,706 | N 8° 33′ 3'' | W 82° 39′ 3'' |
| 463 | Soná Sona,Soná | Panama, Veraguas Province Soná District > Corregimiento Soná | seat of a second-order administrative division population 7,669 | N 8° 0′ 31'' | W 81° 19′ 2'' |
| 464 | Isla German Soldier Cay Cayo Aurec,Cayo Auree,Cayo Soldado Aleman,Cayo Soldado Alemán,German Soldier Cay,Isla German Soldier... | Panama, Bocas del Toro Province | island | N 9° 14′ 28'' | W 82° 9′ 18'' |
| 465 | Islas Secas Islas Secas | Panama, Chiriquí Province | islands | N 7° 58′ 34'' | W 82° 2′ 37'' |
| 466 | San Vicente de Bique Bique,San Vicente de Bique,Sitio Viejo | Panama, Panamá Oeste Province Arraiján District > Corregimiento Vista Alegre | section of populated place population 1,784 | N 8° 54′ 57'' | W 79° 40′ 20'' |
| 467 | Santo Domingo Santo Domingo | Panama, Chiriquí Province Bugaba District > Corregimiento Santo Domingo | seat of a third-order administrative division population 1,216 | N 8° 30′ 37'' | W 82° 42′ 49'' |
| 468 | Santo Domingo Santo Domingo | Panama, Los Santos Province Las Tablas District > Corregimiento Santo Domingo | seat of a third-order administrative division population 1,772 | N 7° 44′ 54'' | W 80° 14′ 29'' |
| 469 | Cerro Santiago Cerro Santiago | Panama, Ngöbe-Buglé Comarca Müna District > Corregimiento Peña Blanca | mountain | N 8° 30′ 8'' | W 81° 44′ 36'' |
| 470 | Isla San Telmo Isla San Telmo | Panama, Panamá | island | N 8° 16′ 34'' | W 78° 50′ 42'' |
| 471 | Santa Rosa Santa Rosa | Panama, Colón Colón District > Corregimiento Cristóbal | populated place | N 9° 11′ 5'' | W 79° 39′ 15'' |
| 472 | Santa Marta Santa Marta | Panama, Chiriquí Province Bugaba District > Corregimiento Santa Marta | seat of a third-order administrative division population 1,952 | N 8° 31′ 22'' | W 82° 42′ 4'' |
| 473 | Santa María Santa Maria,Santa María | Panama, Herrera Province Santa María District > Corregimiento Santa María | seat of a second-order administrative division population 1,679 | N 8° 6′ 50'' | W 80° 39′ 52'' |
| 474 | Santa Clara Santa Clara | Panama, Panamá Oeste Province Arraiján District > Corregimiento Santa Clara | seat of a third-order administrative division population 1,410 | N 9° 2′ 1'' | W 79° 45′ 12'' |
| 475 | Santa Clara Santa Clara | Panama, Coclé Antón District > Corregimiento Río Hato | populated place population 597 | N 8° 22′ 56'' | W 80° 6′ 31'' |
| 476 | Santa Ana Arriba Santa Ana Arriba,Tembladera | Panama, Los Santos Province Los Santos District > Corregimiento Santa Ana | seat of a third-order administrative division population 1,025 | N 7° 56′ 4'' | W 80° 21′ 49'' |
| 477 | Santa Ana Santa Ana | Panama, Los Santos Province Guararé District > Corregimiento El Macano | populated place | N 7° 40′ 18'' | W 80° 24′ 58'' |
| 478 | San San Druy Drury,San San,San San Drui,San San Druy,San San Durui | Panama, Bocas del Toro Province Changuinola District > El Teribe | populated place population 432 | N 9° 25′ 58'' | W 82° 41′ 22'' |
479  | San San Druy San San Druy,San San Durui | Panama, Bocas del Toro Province Changuinola District > El Teribe | locality | N 9° 26′ 31'' | W 82° 40′ 49'' |
| 480 | San Lorenzo San Lorenzo | Panama, Chiriquí Province San Lorenzo District > Corregimiento San Lorenzo | seat of a third-order administrative division population 1,025 | N 8° 18′ 33'' | W 82° 6′ 9'' |
| 481 | San Jose Island Isla San Jose,Isla San José,SIC,San Jose Island | Panama, Panamá Balboa District > Corregimiento Pedro González | island | N 8° 16′ 3'' | W 79° 6′ 31'' |
| 482 | San José San Jose,San José | Panama, Panamá Oeste Province San Carlos District > Corregimiento San José | seat of a third-order administrative division population 1,444 | N 8° 32′ 7'' | W 79° 55′ 24'' |
| 483 | San Francisco San Francisco,San Francisquito | Panama, Panamá Balboa District > Corregimiento San Miguel | locality | N 8° 27′ 41'' | W 78° 55′ 33'' |
| 484 | San Francisco San Francisco | Panama, Veraguas Province San Francisco District > Corregimiento San Francisco | seat of a second-order administrative division population 1,785 | N 8° 14′ 43'' | W 80° 58′ 25'' |
| 485 | San Félix San Felix,San Félix | Panama, Chiriquí Province San Félix District > Corregimiento San Félix | seat of a third-order administrative division population 1,051 | N 8° 17′ 35'' | W 81° 52′ 9'' |
| 486 | San Felipe | Panama, Panamá Panamá District > Corregimiento San Felipe | section of populated place population 3,262 | N 8° 57′ 4'' | W 79° 32′ 14'' |
| 487 | San Andrés San Andreas,San Andres,San Andrés | Panama, Chiriquí Province Bugaba District > Corregimiento San Andrés | seat of a third-order administrative division population 1,152 | N 8° 36′ 7'' | W 82° 43′ 28'' |
488  | Cuenca Salud Cuenca Salud,Salud Basin | Panama, Colón | lake | N 9° 10′ 42'' | W 79° 47′ 38'' |
| 489 | Salitre Desembocadura de Salitre,Salitre | Panama, Ngöbe-Buglé Comarca Nole Duima District > Corregimiento Hato Chamí | locality | N 8° 24′ 39'' | W 81° 48′ 8'' |
| 490 | Sal Creek Quebrada Ccader,Salt River | Panama, Bocas del Toro Province Bocas del Toro District > Corregimiento Bastimentos | populated place population 150 | N 9° 18′ 0'' | W 82° 6′ 0'' |
| 491 | Salamanca Salamanca | Panama, Colón Colón District > Corregimiento Salamanca | populated place population 981 | N 9° 20′ 10'' | W 79° 36′ 10'' |
| 492 | Punta Rodríguez Big Bight,Ensenada Grande,Jack Point,Puerto Laurel,Punta Rodriguez,Punta Rodríguez | Panama, Bocas del Toro Province Bocas del Toro District > Tierra Oscura | point | N 9° 14′ 25'' | W 82° 17′ 36'' |
| 493 | Punta Róbalo Punta Robalo,Punta Rovalo,Punta Róbalo | Panama, Bocas del Toro Province Chiriquí Grande District > Corregimiento Punta Róbalo | point | N 9° 2′ 18'' | W 82° 14′ 51'' |
| 494 | Valle de Riscó Risco,Valle de Risco,Valle de Riscó,Valle del Risco | Panama, Bocas del Toro Province Almirante > Valle de Riscó | seat of a third-order administrative division population 1,171 | N 9° 13′ 52'' | W 82° 25′ 46'' |
| 495 | Río Sereno Rio Sereno,Río Sereno,Sereno | Panama, Chiriquí Province Renacimiento District > Corregimiento Río Sereno | seat of a second-order administrative division population 1,368 | N 8° 49′ 10'' | W 82° 51′ 37'' |
| 496 | Río Ostión Rio Ostion,Rio Ostion Afuera,Río Ostión,Río Ostión Afuera | Panama, Panamá Balboa District > Corregimiento San Miguel | locality | N 8° 27′ 30'' | W 78° 53′ 59'' |
| 497 | Río Iglesias Bajos de Iglesia,Bajos de Iglesias,Rio Iglesia,Rio Iglesias,Río Iglesia,Río Iglesias | Panama, Darién Santa Fe > Corregimiento Río Iglesias | populated place | N 8° 23′ 49'' | W 78° 0′ 37'' |
| 498 | Río Grande Rio Grande,Río Grande | Panama, Coclé Penonomé District > Corregimiento Río Grande | seat of a third-order administrative division population 1,070 | N 8° 25′ 54'' | W 80° 29′ 13'' |
| 499 | Gatún Gatun,Gatún,Rio Gatun,Río Gatún | Panama, Colón Colón District > Corregimiento Cristóbal | populated place population 1,553 | N 9° 17′ 20'' | W 79° 46′ 4'' |
| 500 | Río de Jesús Rio de Jesus,Río de Jesús | Panama, Veraguas Province Río de Jesús District > Corregimiento Río de Jesús | seat of a second-order administrative division population 1,060 | N 7° 59′ 2'' | W 81° 9′ 41'' |
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